After maturation, in primary lymphoid organs, thelymphocytes migrate for interaction with antigens tosecondary

After maturation, in primary lymphoid organs, thelymphocytes migrate for interaction with antigens tosecondary lymphoid organ(s)/tissue(s) like:A. thymusB. bone marrowC. spleenD. lymph nodesE. Peyer’s patchesChoose the correct answer from the options givenbelow:

Answer

Secondary Lymphoid Organs Explanation

✅ Correct Option: (4) C, D, E only

Immune System Overview: The immune system is divided into primary and secondary lymphoid organs, each having a distinct role in lymphocyte development and function.

🧪 Primary Lymphoid Organs

These are the sites where lymphocytes mature and become antigen-sensitive:

  • Bone marrow – site of B cell maturation
  • Thymus – site of T cell maturation

These are not involved in direct antigen interaction.

🛡️ Secondary Lymphoid Organs / Tissues

After maturation, lymphocytes migrate to these sites to encounter antigens and initiate immune responses:

  • Spleen
  • Lymph nodes
  • Peyer’s patches (in small intestine)

These are the sites of antigen–lymphocyte interaction where effector cells are formed.

📌 Final Matching:

  • A. Thymus – Primary
  • B. Bone marrow – Primary
  • C. Spleen – Secondary
  • D. Lymph nodes – Secondary
  • E. Peyer’s patches – Secondary

✅ Therefore, the correct answer is:

(4) C, D, E only

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