Answer
Streptokinase: A Clot-Dissolving Enzyme
Definition and Source:
Streptokinase is an enzyme produced by the bacterium Streptococcus. It is a fibrinolytic agent, which means it helps break down fibrin, a protein involved in blood clotting.
Medical Application:
Streptokinase is commonly referred to as a “clot buster” because of its ability to dissolve blood clots. It is used in the treatment of myocardial infarction (heart attack), where blood clots block coronary arteries and reduce blood flow to the heart muscle.
Mechanism of Action:
Streptokinase activates plasminogen, a precursor protein found in the blood, converting it into plasmin, an enzyme that breaks down fibrin and dissolves clots.
Clinical Importance:
By dissolving clots, streptokinase helps restore normal blood flow, minimizing damage to the heart tissue and improving the survival chances of patients experiencing a heart attack.
Conclusion:
The use of streptokinase is a significant medical advancement in emergency cardiac care, particularly in managing acute myocardial infarction.