Which of the following hormones released from the pituitary is actually synthesized in the hypothalamus?

Answer

Question:

Which of the following hormones released from the pituitary is actually synthesized in the hypothalamus?

Options:

1. Luteinizing hormone (LH)
2. Anti-diuretic hormone (ADH)
3. Follicle-stimulating hormone (FSH)
4. Adrenocorticotropic hormone (ACTH)

Explanation:

The question asks which hormone, although released from the pituitary gland, is actually synthesized in the hypothalamus.

• LH (Luteinizing hormone) – Synthesized and released by the anterior pituitary. Not synthesized in the hypothalamus.
• ADH (Anti-diuretic hormone) – Also known as vasopressin. Synthesized in the hypothalamus (in the supraoptic and paraventricular nuclei) and transported to the posterior pituitary for release into the bloodstream.
• FSH (Follicle-stimulating hormone) – Produced and released by the anterior pituitary. Not synthesized in the hypothalamus.
• ACTH (Adrenocorticotropic hormone) – Produced by the anterior pituitary. Not synthesized in the hypothalamus.

✅ Correct Answer: (2) Anti-diuretic hormone (ADH)

Reason: ADH is the only hormone listed that is synthesized in the hypothalamus but released by the pituitary gland.